The steroid biotransformation genes in genomes of mycobacteria

نویسندگان

  • Ewa Bartnik
  • Jarosław Dziadek
  • Anna Brzostek
  • Bożena Dziadek
  • Anna Rumijowska-Galewicz
  • Małgorzata Korycka-Machała
  • Dagmara Jakimowicz
  • Jolanta Zakrzewska-Czerwińska
چکیده

The sequence of the human mitochondrial genome was established almost 25 years ago and has been used in analysis of human population migrations, forensic medicine, longevity studies and in investigation of the causes of mitochondrial diseases.It is a small compact genome of 16.5 kb containing information about 13 protens, 2 rRNAs and 22 tRNAs.There are many variants (haplogroups) of the human mitochondrial genomeand some of them have been associated — for some populations — with longevity orcertain mitochondrial disease. Many of these associations were only detected for certain populations. I will discuss the mitochondrial DNA haplogroups in the Polishpopulation and the association of certain mitohcondrial haplogroups with a mitochondrial blindness, Leber Hereditaty Optic Neuropahy.

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تاریخ انتشار 2005